MonosaccharideBuilder allows querying the database by a specific monosaccharide without or with limited knowledge of its notation, but with knowledge of its chemical structure. It starts from a standard carbohydrate backbone of a given size and provide information on stereochemistry, core modifications, ring closure or substituents step by step. Alternatively, Monosaccharide Builder can be initialized using a monosaccharide name. This approach is helpful to explore changes to a given residue, such as "What monosaccharide do I get when changing the stereochemistry of position 3 of b-D-Glcp?"